Dietary Fiber-Derived Microbial Butyrate Suppresses ILC2-Dependent Airway Inflammation in COPD

Group 2 innate lymphoid cells (ILC2) strongly modulate COPD pathogenesis. However, the significance of microbiota in ILC2s remains unelucidated. Herein, we investigated the immunomodulatory role of short-chain fatty acids (SCFAs) in regulating ILC2-associated airway inflammation and explores its ass...

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Bibliographic Details
Main Authors: Min Jiang, Jing Wang, Zheng Li, Dan Xu, Jing Jing, Fengsen Li, Jianbing Ding, Qifeng Li
Format: Article
Language:English
Published: Hindawi Limited 2024-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2024/6263447