Bacterial PncA improves diet-induced NAFLD in mice by enabling the transition from nicotinamide to nicotinic acid

Bacterial nicotinamidase/pyrazinamidase PncA increases host nicotinamide adenine dinucleotide (NAD+) levels and ameliorates diet-induced non-alcoholic fatty liver disease (NAFLD) in mice.

Bibliographic Details
Main Authors: Shengyu Feng, Liuling Guo, Hao Wang, Shanshan Yang, Hailiang Liu
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04613-8