Bacterial PncA improves diet-induced NAFLD in mice by enabling the transition from nicotinamide to nicotinic acid
Bacterial nicotinamidase/pyrazinamidase PncA increases host nicotinamide adenine dinucleotide (NAD+) levels and ameliorates diet-induced non-alcoholic fatty liver disease (NAFLD) in mice.
Main Authors: | Shengyu Feng, Liuling Guo, Hao Wang, Shanshan Yang, Hailiang Liu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-04613-8 |
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