Development of New Thiophene-Containing Triaryl Pyrazoline Derivatives as PI3Kγ Inhibitors
A series of new thiophene-containing triaryl pyrazoline derivatives, <b>3a</b>–<b>3t</b>, were synthesized and evaluated regarding PI3K inhibition activity and anti-tumor potency based on a trial of introducing significant moieties, including pyrazoline and thiophene, and sim...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/8/2404 |