A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans
When mutations have small effects on fitness, population size plays an important role in determining the amount and nature of deleterious genetic variation. The extent to which recent population size changes have impacted deleterious variation in humans has been a question of considerable interest a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Oxford University Press
2017-03-01
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| Series: | G3: Genes, Genomes, Genetics |
| Subjects: | |
| Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.117.039651 |