Ligand-gated mechanisms leading to ictogenesis in focal epileptic disorders

We review here the neuronal mechanisms that cause seizures in focal epileptic disorders and, specifically, those involving limbic structures that are known to be implicated in human mesial temporal lobe epilepsy. In both epileptic patients and animal models, the initiation of focal seizures - which...

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Bibliographic Details
Main Authors: Massimo Avoli, Li-Yuan Chen, Graziella Di Cristo, Laura Librizzi, Paolo Scalmani, Zahra Shiri, Laura Uva, Marco de Curtis, Maxime Lévesque
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123001110