Rare Occurrence of Aristolochic Acid Mutational Signatures in Oro-Gastrointestinal Tract Cancers

Rare Occurrence of Aristolochic Acid Mutational Signatures in Oro-Gastrointestinal Tract Cancers

Background: Aristolochic acids (AAs) are potent mutagens commonly found in herbal plant-based remedies widely used throughout Asian countries. Patients and Methods: To understand whether AA is involved in the tumorigenesis of the oro-gastrointestinal tract, we used whole-exome sequencing to profile...

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Bibliographic Details
Main Authors: Abner Herbert Lim, Jason Yongsheng Chan, Ming-Chin Yu, Tsung-Han Wu, Jing Han Hong, Cedric Chuan Young Ng, Zhen Jie Low, Wei Liu, Rajasegaran Vikneswari, Pin-Cheng Sung, Wen-Lang Fan, Bin Tean Teh, Sen-Yung Hsieh
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
carcinogens
mutagenesis
next generation sequencing
genomics
aristolochic acid
Online Access:https://www.mdpi.com/2072-6694/14/3/576

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https://www.mdpi.com/2072-6694/14/3/576

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