How to assess hypercoagulability in heparin-induced thrombocytopenia? Biomarkers of potential value to support therapeutic intensity of non-heparin anticoagulation

How to assess hypercoagulability in heparin-induced thrombocytopenia? Biomarkers of potential value to support therapeutic intensity of non-heparin anticoagulation

Abstract Background In case of heparin-induced thrombocytopenia (HIT), the switch to a non-heparin anticoagulant is mandatory, at a therapeutic dose. Such a treatment has limitations though, especially for patients with renal and/or hepatic failure. Candidate laboratory tests could detect the more c...

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Bibliographic Details
Main Authors: Antoine Barocas, Philippe Savard, Audrey Carlo, Thomas Lecompte, Emmanuel de Maistre
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Thrombosis Journal
Subjects:
Heparin induced thrombocytopenia
Thrombin generation
Fibrin monomers
Procoagulant vesicles
Thrombosis
Anticoagulant treatment
Online Access:https://doi.org/10.1186/s12959-023-00546-8

Internet

https://doi.org/10.1186/s12959-023-00546-8

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