Efficacy and safety of lenvatinib–transcatheter arterial chemoembolisation sequential therapy followed by surgical resection for intermediate-stage hepatocellular carcinoma beyond Up-to-7 criteria: a study protocol for a multicentre, single-arm, prospective study

Efficacy and safety of lenvatinib–transcatheter arterial chemoembolisation sequential therapy followed by surgical resection for intermediate-stage hepatocellular carcinoma beyond Up-to-7 criteria: a study protocol for a multicentre, single-arm, prospective study

Introduction The feasibility and efficacy of surgical resection following systemic therapy for intermediate-stage hepatocellular carcinoma (HCC) beyond the Up-to-7 criteria is unclear. The combination of lenvatinib (LEN) and transcatheter arterial chemoembolisation (TACE), termed LEN–TACE sequential...

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Bibliographic Details
Main Authors: Hiroshi Aikata, Hiroshi Sakai, Michio Imamura, Masahiro Ohira, Tsuyoshi Kobayashi, Ryosuke Nakano, Naoki Tanimine, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Hideki Ohdan, Ko Oshita, Yosuke Namba, Sotaro Fukuhara, Keiso Matsubara, Daisuke Takei, Wataru Okamoto, Takashi Nakahara, Tomokazu Kawaoka
Format: Article
Language:English
Published: BMJ Publishing Group 2023-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/10/e073797.full

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https://bmjopen.bmj.com/content/13/10/e073797.full

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