Resolution of a Metastable Racemic Compound of Anhydrous Phencyphos by Hydrate Formation

The resolution of 2-hydroxy-5,5-dimethyl-4-phenyl-1,3,2-dioxaphosphorinan 2-oxide (phencyphos) was achieved by dissolution of anhydrous racemic phencyphos, a racemic compound, accompanied by simultaneous secondary nucleation of the dissolved racemate on to enantiopure seeds of phencyphos hydrate, a...

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Bibliographic Details
Main Authors: Michel Leeman, Richard M. Kellogg
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/11/10/1225