Regulation of Sox6 by cyclin dependent kinase 5 in brain.

Cyclin dependent kinase 5 (Cdk5) is a proline-directed Ser/Thr kinase involved in various biological functions during normal brain development and neurodegeneration. In brain, Cdk5 activity is specific to post-mitotic neurons, due to neuronal specific expression of its activator p35. The biological...

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Bibliographic Details
Main Authors: Parvathi Rudrabhatla, Elias Utreras, Howard Jaffe, Ashok B Kulkarni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3963837?pdf=render