Precise mapping of the CD95 pre-ligand assembly domain.

Precise mapping of the CD95 pre-ligand assembly domain.

Pre-association of CD95 at the plasma membrane is mandatory for efficient death receptor signaling. This homotrimerization occurs through self-association of an extracellular domain called the pre-ligand assembly domain (PLAD). Using novel molecular and cellular tools, we confirmed that CD95-PLAD is...

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Bibliographic Details
Main Authors: Valérie Edmond, Benoist Ghali, Aubin Penna, Jean-Luc Taupin, Sophie Daburon, Jean-François Moreau, Patrick Legembre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3457997?pdf=render

Internet

http://europepmc.org/articles/PMC3457997?pdf=render

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