Activity dependent dissociation of the Homer1 interactome

Abstract Neurons encode information by rapidly modifying synaptic protein complexes, which changes the strength of specific synaptic connections. Homer1 is abundantly expressed at glutamatergic synapses, and is known to alter its binding to metabotropic glutamate receptor 5 (mGlu5) in response to sy...

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Bibliographic Details
Main Authors: Mason Stillman, Jonathan D. Lautz, Richard S. Johnson, Michael J. MacCoss, Stephen E. P. Smith
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-07179-3