Upregulation of complement proteins in lung cancer cells mediates tumor progression

Upregulation of complement proteins in lung cancer cells mediates tumor progression

IntroductionIn vivo, cancer cells respond to signals from the tumor microenvironment resulting in changes in expression of proteins that promote tumor progression and suppress anti-tumor immunity. This study employed an orthotopic immunocompetent model of lung cancer to define pathways that are alte...

Full description

Bibliographic Details
Main Authors: Emily K. Kleczko, Joanna M. Poczobutt, Andre C. Navarro, Jennifer Laskowski, Amber M. Johnson, Sean P. Korpela, Natalia J. Gurule, Lynn E. Heasley, Katharina Hopp, Mary C.M. Weiser-Evans, Elizabeth B. Gottlin, Ryan T. Bushey, Michael J. Campa, Edward F. Patz, Joshua M. Thurman, Raphael A. Nemenoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
complement
NSCLC
tumor microenvironment
RNA sequencing
factor H (FH)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1045690/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1045690/full

Similar Items