Integrative whole-genome and transcriptome analysis of HER2-amplified metastatic breast cancer
Abstract Background In breast cancer, the advent of anti-HER2 therapies has made HER2+ tumors a highly relevant subgroup. However, the exact characteristics which prohibit clinical response to anti-HER2 therapies and drive disease progression are not yet fully known. Integrative whole-genome and tra...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-11-01
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Series: | Breast Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13058-023-01743-z |