Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage

Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage

Summary: Investigations of the human germline and programming are challenging because of limited access to embryonic material. However, the pig as a model may provide insights into transcriptional network and epigenetic reprogramming applicable to both species. Here we show that, during the pre- and...

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Bibliographic Details
Main Authors: Qifan Zhu, Fei Sang, Sarah Withey, Walfred Tang, Sabine Dietmann, Doris Klisch, Priscila Ramos-Ibeas, Haixin Zhang, Cristina E. Requena, Petra Hajkova, Matt Loose, M. Azim Surani, Ramiro Alberio
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Cell Reports
Subjects:
germ cells
DNA demethylation
pig
escapees
X-chromosome reactivation
single-cell RNA-seq
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721000486

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http://www.sciencedirect.com/science/article/pii/S2211124721000486

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