Distinct Expression Patterns of Genes Coding for Biological Response Modifiers Involved in Inflammatory Responses and Development of Fibrosis in Chronic Hepatitis C: Upregulation of SMAD-6 and MMP-8 and Downregulation of CAV-1, CTGF, CEBPB, PLG, TIMP-3, MMP-1, ITGA-1, ITGA-2 and LOX

Distinct Expression Patterns of Genes Coding for Biological Response Modifiers Involved in Inflammatory Responses and Development of Fibrosis in Chronic Hepatitis C: Upregulation of SMAD-6 and MMP-8 and Downregulation of CAV-1, CTGF, CEBPB, PLG, TIMP-3, MMP-1, ITGA-1, ITGA-2 and LOX

<i>Background and Objectives</i>: The aim of this study was to analyze the expression of genes on transcriptomic levels involved in inflammatory immune responses and the development of fibrosis in patients with chronic hepatitis C. <i>Materials and Methods</i>: Expression pat...

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Bibliographic Details
Main Authors: Leona Radmanić, Petra Korać, Lana Gorenec, Petra Šimičić, Kristian Bodulić, Adriana Vince, Snježana Židovec Lepej
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Medicina
Subjects:
hepatitis C infection
fibrosis
SMAD-6
CAV-1
gene expression
Online Access:https://www.mdpi.com/1648-9144/58/12/1734

Internet

https://www.mdpi.com/1648-9144/58/12/1734

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