Canagliflozin combined with aerobic exercise protects against chronic heart failure in rats

Summary: To determine the efficacy and potential protective mechanism of canagliflozin combined with aerobic exercise in treating chronic heart failure (CHF). Isoproterenol was injected into rats to create CHF models. The rats were then subsequently divided into saline, canagliflozin (3 mg/kg/d), ae...

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Bibliographic Details
Main Authors: Helin Sun, Bingyu Du, Hui Fu, Zhaodi Yue, Xueyin Wang, Shaohong Yu, Zhongwen Zhang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224002359