A reverse phase protein array based phospho-antibody characterization approach and its applicability for clinical derived tissue specimens

Abstract Systematic quantification of phosphoprotein within cell signaling networks in solid tissues remains challenging and precise quantification in large scale samples has great potential for biomarker identification and validation. We developed a reverse phase protein array (RPPA) based phosphor...

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Bibliographic Details
Main Authors: Nan Wang, Li Zhang, Qi Ying, Zhentao Song, Aiping Lu, Achim Treumann, Zhaojian Liu, Tao Sun, Zhiyong Ding
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-26715-9