Probing GFP Chromophore Analogs as Anti-HIV Agents Targeting LTR-III G-Quadruplex

Probing GFP Chromophore Analogs as Anti-HIV Agents Targeting LTR-III G-Quadruplex

Green fluorescent protein (GFP) chromophore and its congeners draw significant attention mostly for bioimaging purposes. In this work we probed these compounds as antiviral agents. We have chosen LTR-III DNA G4, the major G-quadruplex (G4) present in the long terminal repeat (LTR) promoter region of...

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Bibliographic Details
Main Authors: Dmitriy Y. Ryazantsev, Mikhail Yu. Myshkin, Vera A. Alferova, Vladimir B. Tsvetkov, Elena Y. Shustova, Polina N. Kamzeeva, Polina V. Kovalets, Elvira R. Zaitseva, Nadezhda S. Baleeva, Timofei S. Zatsepin, Zakhar O. Shenkarev, Mikhail S. Baranov, Liubov I. Kozlovskaya, Andrey V. Aralov
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
G-quadruplex
FRET-melting
green fluorescent protein (GFP) chromophore
antiviral activity
cytotoxicity
Online Access:https://www.mdpi.com/2218-273X/11/10/1409

Internet

https://www.mdpi.com/2218-273X/11/10/1409

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