Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture.

The human malaria parasite Plasmodium falciparum is responsible for the majority of mortality and morbidity caused by malaria infection and differs from other human malaria species in the degree of accumulation of parasite-infected red blood cells in the microvasculature, known as cytoadherence or s...

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Main Authors: Basim Othman, Leo Zeef, Tadge Szestak, Zineb Rchiad, Janet Storm, Caroline Askonas, Rohit Satyam, Aymen Madkhali, Michael Haley, Simon Wagstaff, Kevin Couper, Arnab Pain, Alister Craig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295053&type=printable