Universal method for the isolation of microvessels from frozen brain tissue: A proof-of-concept multiomic investigation of the neurovasculature

Universal method for the isolation of microvessels from frozen brain tissue: A proof-of-concept multiomic investigation of the neurovasculature

The neurovascular unit, comprised of vascular cell types that collectively regulate cerebral blood flow to meet the needs of coupled neurons, is paramount for the proper function of the central nervous system. The neurovascular unit gatekeeps blood-brain barrier properties, which experiences impairm...

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Bibliographic Details
Main Authors: Marina Wakid, Daniel Almeida, Zahia Aouabed, Reza Rahimian, Maria Antonietta Davoli, Volodymyr Yerko, Elena Leonova-Erko, Vincent Richard, René Zahedi, Christoph Borchers, Gustavo Turecki, Naguib Mechawar
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Neurovascular unit
Blood-Brain Barrier
Microvessels
Postmortem
RNA sequencing
LC-MS/MS
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354623000984

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http://www.sciencedirect.com/science/article/pii/S2666354623000984

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