Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer

Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer

Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signatures’ that have led to key insights into cancer etiolog...

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Bibliographic Details
Main Authors: Bahman Afsari, Albert Kuo, YiFan Zhang, Lu Li, Kamel Lahouel, Ludmila Danilova, Alexander Favorov, Thomas A Rosenquist, Arthur P Grollman, Ken W Kinzler, Leslie Cope, Bert Vogelstein, Cristian Tomasetti
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
mutational signature
somatic mutations
obesity
environmental exposures
carcinogens
Online Access:https://elifesciences.org/articles/61082

Internet

https://elifesciences.org/articles/61082

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