Systems Cancer Biology and the Controlling Mechanisms for the J-Shaped Cancer dose Response: Towards Relaxing the LNT Hypothesis
The hormesis phenomena or J-shaped dose response have been accepted as a common phenomenon regardless of the involved biological model, endpoint measured and chemical class/physical stressor. This paper first introduced a mathematical dose response model based on systems biology approach. It links m...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2013-07-01
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Series: | Dose-Response |
Online Access: | https://doi.org/10.2203/dose-response.12-037.Lou |