Evaluation of cortical bone remodeling in canines treated with daily and weekly administrations of teriparatide by establishing AI-driven morphometric analyses and GIS-based spatial mapping

Evaluation of cortical bone remodeling in canines treated with daily and weekly administrations of teriparatide by establishing AI-driven morphometric analyses and GIS-based spatial mapping

Larger animal models with a well-developed Haversian system, as observed in humans, are ideal to analyze cortical bone remodeling in pharmacological studies of anti-osteoporosis drugs, although they have some limitations in controlling individual variability in size, weight, age, and number. This st...

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Bibliographic Details
Main Authors: Marie Hoshi-Numahata, Aya Takakura, Atsuko Nakanishi-Kimura, Haruhisa Watanabe, Kentaro Takada, Mai Nishiura, Yoshiaki Sato, Ryoko Takao-Kawabata, Tadahiro Iimura
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Bone Reports
Subjects:
Teriparatide
PTH
Cortical bone
Haversian canal
Artificial intelligence
Geographical information system
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187223000669

Internet

http://www.sciencedirect.com/science/article/pii/S2352187223000669

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