Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate

Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate

Gut microbiota-dependent Trimethylamine-N-oxide (TMAO) has been reported to be strongly linked to renal function and to increased cardiovascular events in the general population and in Chronic Kidney Disease (CKD) patients. Considering the lack of data assessing renal handling of TMAO, we conducted...

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Bibliographic Details
Main Authors: Caroline C. Pelletier, Mikael Croyal, Lavinia Ene, Audrey Aguesse, Stephanie Billon-Crossouard, Michel Krempf, Sandrine Lemoine, Fitsum Guebre-Egziabher, Laurent Juillard, Christophe O. Soulage
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Toxins
Subjects:
uremic toxin
trimethylamine-n-oxide
renal clearance
chronic kidney disease
hemodialysis
Online Access:https://www.mdpi.com/2072-6651/11/11/635

Internet

https://www.mdpi.com/2072-6651/11/11/635

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