ETV2/ER71 regulates the generation of FLK1+ cells from mouse embryonic stem cells through miR-126-MAPK signaling

ETV2/ER71 regulates the generation of FLK1+ cells from mouse embryonic stem cells through miR-126-MAPK signaling

Abstract Previous studies including ours have demonstrated a critical function of the transcription factor ETV2 (ets variant 2; also known as ER71) in determining the fate of cardiovascular lineage development. However, the underlying mechanisms of ETV2 function remain largely unknown. In this study...

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Bibliographic Details
Main Authors: Ju Young Kim, Dong Hun Lee, Joo Kyung Kim, Hong Seo Choi, Bhakti Dwivedi, Manali Rupji, Jeanne Kowalski, Stefan J. Green, Heesang Song, Won Jong Park, Ji Young Chang, Tae Min Kim, Changwon Park
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Stem Cell Research & Therapy
Subjects:
ETV2/ER71
FLK1+ cells
miR-126
EGFL7
Embryonic stem cells
Online Access:http://link.springer.com/article/10.1186/s13287-019-1466-8

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http://link.springer.com/article/10.1186/s13287-019-1466-8

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