Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC <sup>min</sup>/J Mice

Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC <sup>min</sup>/J Mice

The Eph receptors are the largest receptors tyrosine kinases (RTKs) family in humans and together with ephrin ligands constitute a complex cellular communication system often dysregulated in many tumors. The role of the Eph-ephrin system in colorectal cancer (CRC) has been investigated and different...

Full description

Bibliographic Details
Main Authors: Miriam Corrado, Carmine Giorgio, Elisabetta Barocelli, Giuseppe Vittucci Marzetti, Anna Maria Cantoni, Rosanna Di Lecce, Matteo Incerti, Riccardo Castelli, Alessio Lodola, Massimiliano Tognolini
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceuticals
Subjects:
Eph-ephrin system
EphA receptors
EphB receptors
Eph antagonist
UniPR129
APC <sup>min</sup>/J mice
Online Access:https://www.mdpi.com/1424-8247/13/4/69

Internet

https://www.mdpi.com/1424-8247/13/4/69

Similar Items