Epigenetic Suppression of the IL-7 Pathway in Progressive Glioblastoma

Epigenetic Suppression of the IL-7 Pathway in Progressive Glioblastoma

Background: Immune evasion in glioblastoma (GBM) shields cancer cells from cytotoxic immune response. Methods: We investigated CpG methylation in promoters, genes, and pathways in 22 pairs of formalin-fixed paraffin-embedded sequential (FFPE) GBM using restricted resolution bisulfite sequencing (RRB...

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Bibliographic Details
Main Authors: Marton Tompa, Zoltan Kraboth, Bence Galik, Bela Kajtar, Attila Gyenesei, Bernadette Kalman
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
glioblastoma
immune evasion
epigenomics
CpG methylation
interleukin 7 pathway
Online Access:https://www.mdpi.com/2227-9059/10/9/2174

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https://www.mdpi.com/2227-9059/10/9/2174

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