Genome-wide analysis identifies Homothorax and Extradenticle as regulators of insulin in Drosophila Insulin-Producing cells.

Drosophila Insulin-Producing Cells (IPCs) are the main production site of the Drosophila Insulin-like peptides or dilps which have key roles in regulating growth, development, reproduction, lifespan and metabolism. To better understand the signalling pathways and transcriptional networks that are ac...

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Bibliographic Details
Main Authors: Mattias Winant, Kurt Buhler, Jason Clements, Sofie De Groef, Korneel Hens, Veerle Vulsteke, Patrick Callaerts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010380