Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment

PET imaging in human participants revealed that D1 and D2 dopamine receptor availability was associated with eye-blink rates following treatment with oral methylphenidate, but not a placebo.

Bibliographic Details
Main Authors: Şükrü B. Demiral, Peter Manza, Erin Biesecker, Corinde Wiers, Ehsan Shokri-Kojori, Katherine McPherson, Evan Dennis, Allison Johnson, Dardo Tomasi, Gene-Jack Wang, Nora D. Volkow
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03979-5