Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment
PET imaging in human participants revealed that D1 and D2 dopamine receptor availability was associated with eye-blink rates following treatment with oral methylphenidate, but not a placebo.
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-09-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03979-5 |
| _version_ | 1811236423512096768 |
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| author | Şükrü B. Demiral Peter Manza Erin Biesecker Corinde Wiers Ehsan Shokri-Kojori Katherine McPherson Evan Dennis Allison Johnson Dardo Tomasi Gene-Jack Wang Nora D. Volkow |
| author_facet | Şükrü B. Demiral Peter Manza Erin Biesecker Corinde Wiers Ehsan Shokri-Kojori Katherine McPherson Evan Dennis Allison Johnson Dardo Tomasi Gene-Jack Wang Nora D. Volkow |
| author_sort | Şükrü B. Demiral |
| collection | DOAJ |
| description | PET imaging in human participants revealed that D1 and D2 dopamine receptor availability was associated with eye-blink rates following treatment with oral methylphenidate, but not a placebo. |
| first_indexed | 2024-04-12T12:09:41Z |
| format | Article |
| id | doaj.art-eb8bf127aee141bca5ac632e6ce5563f |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-12T12:09:41Z |
| publishDate | 2022-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-eb8bf127aee141bca5ac632e6ce5563f2022-12-22T03:33:38ZengNature PortfolioCommunications Biology2399-36422022-09-015111010.1038/s42003-022-03979-5Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatmentŞükrü B. Demiral0Peter Manza1Erin Biesecker2Corinde Wiers3Ehsan Shokri-Kojori4Katherine McPherson5Evan Dennis6Allison Johnson7Dardo Tomasi8Gene-Jack Wang9Nora D. Volkow10National Institute on Alcohol Abuse and AlcoholismNational Institute on Alcohol Abuse and AlcoholismNational Institute on Alcohol Abuse and AlcoholismDepartment of Psychiatry, University of PennsylvaniaNational Institute on Alcohol Abuse and AlcoholismNational Institute on Alcohol Abuse and AlcoholismNational Institute on Alcohol Abuse and AlcoholismNational Institute on Alcohol Abuse and AlcoholismNational Institute on Alcohol Abuse and AlcoholismNational Institute on Alcohol Abuse and AlcoholismNational Institute on Drug AbusePET imaging in human participants revealed that D1 and D2 dopamine receptor availability was associated with eye-blink rates following treatment with oral methylphenidate, but not a placebo.https://doi.org/10.1038/s42003-022-03979-5 |
| spellingShingle | Şükrü B. Demiral Peter Manza Erin Biesecker Corinde Wiers Ehsan Shokri-Kojori Katherine McPherson Evan Dennis Allison Johnson Dardo Tomasi Gene-Jack Wang Nora D. Volkow Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment Communications Biology |
| title | Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment |
| title_full | Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment |
| title_fullStr | Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment |
| title_full_unstemmed | Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment |
| title_short | Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment |
| title_sort | striatal d1 and d2 receptor availability are selectively associated with eye blink rates after methylphenidate treatment |
| url | https://doi.org/10.1038/s42003-022-03979-5 |
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