Crystal Structure and Sequence Analysis of N<sup>5</sup>, N<sup>10</sup>-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase Enzyme from <i>Porphyromonas gingivalis</i>

The methylenetetrahydrofolate dehydrogenase–cyclohydrolase (FolD) enzyme has a dual activity of N5,N10-methylenetetrahydrofolate dehydrogenase and cyclohydrolase. This enzyme plays a critical role in the chemical modification of tetrahydrofolate, which is an important coenzyme involved in the synthe...

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Bibliographic Details
Main Authors: Sehyeok Im, Hackwon Do, Jisub Hwang, Youn-Soo Shim, Jun Hyuck Lee
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/13/10/1489