Estimating sensitivity and specificity of diagnostic tests using latent class models that account for conditional dependence between tests: a simulation study

Abstract Background Latent class models are increasingly used to estimate the sensitivity and specificity of diagnostic tests in the absence of a gold standard, and are commonly fitted using Bayesian methods. These models allow us to account for ‘conditional dependence’ between two or more diagnosti...

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Bibliographic Details
Main Authors: Suzanne H. Keddie, Oliver Baerenbold, Ruth H. Keogh, John Bradley
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-023-01873-0