Intranasal PAMAM-G3 scavenges cell-free DNA attenuating the allergic airway inflammation

Abstract Allergic airway inflammation (AAI), including allergic rhinitis (AR) and allergic asthma, is driven by epithelial barrier dysfunction and type 2 inflammation. However, the underlying mechanism remains uncertain and available treatments are constrained. Consequently, we aim to explore the ro...

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Bibliographic Details
Main Authors: Xiumin Chen, Changhui Chen, Zhaoxu Tu, Zeling Guo, Tong Lu, Jian Li, Yihui Wen, Dehua Chen, Wenbin Lei, Weiping Wen, Hang Li
Format: Article
Language:English
Published: Nature Publishing Group 2024-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01980-x