Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation

Heat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation

Abstract Declined numbers and weakened functions of intestinal stem cells (ISCs) impair the integrity of the intestinal epithelium during aging. However, the impact of intestinal microbiota on ISCs in this process is unclear. Here, using premature aging mice (telomerase RNA component knockout, Terc...

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Bibliographic Details
Main Authors: Yadong Qi, Jiamin He, Yawen Zhang, Qiwei Ge, Qiwen Wang, Luyi Chen, Jilei Xu, Lan Wang, Xueqin Chen, Dingjiacheng Jia, Yifeng Lin, Chaochao Xu, Ying Zhang, Tongyao Hou, Jianmin Si, Shujie Chen, Liangjing Wang
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41827-0

Internet

https://doi.org/10.1038/s41467-023-41827-0

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