GPER-mediated inhibition of astrocyte activation mitigates retinal neovascularization in oxygen-induced retinopathy mice

GPER-mediated inhibition of astrocyte activation mitigates retinal neovascularization in oxygen-induced retinopathy mice

Objective To investigate the mechanism by which G protein-coupled estrogen receptor (GPER) reduces retinal neovascularisation in oxygen-induced retinopathy (OIR) in newborn mice. Methods A total of 42 newborn mice were randomly divided into normoxic control group (n=11), OIR group (n=11), G-1(GPER a...

Full description

Bibliographic Details
Main Authors: WANG Xuan, YE Jian, LIU Wei
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2024-06-01
Series:陆军军医大学学报
Subjects:
retinopathy of prematurity
newborn mouse model of oxygen-induced retinopathy
astrocytes
inflammatory factors
g protein-coupled estrogen receptor
Online Access:http://aammt.tmmu.edu.cn/html/202312090.htm

Internet

http://aammt.tmmu.edu.cn/html/202312090.htm

Similar Items