Strategic Decoy Peptides Interfere with MSI1/AGO2 Interaction to Elicit Tumor Suppression Effects

Strategic Decoy Peptides Interfere with MSI1/AGO2 Interaction to Elicit Tumor Suppression Effects

Peptide drugs that target protein–protein interactions have attracted mounting research efforts towards clinical developments over the past decades. Increasing reports have indicated that expression of Musashi 1 (MSI1) is tightly correlated to high grade of cancers as well as enrichment of cancer st...

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Main Authors: Yi-Ping Yang, Andy Chi-Lung Lee, Liang-Ting Lin, Yi-Wei Chen, Pin-I Huang, Hsin-I Ma, Yi-Chen Chen, Wen-Liang Lo, Yuan-Tzu Lan, Wen-Liang Fang, Chien-Ying Wang, Yung-Yang Liu, Po-Kuei Hsu, Wen-Chang Lin, Chung-Pin Li, Ming-Teh Chen, Chian-Shiu Chien, Mong-Lien Wang
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
decoy peptide
MSI1 C-terminus
MSI1/AGO2 disruption
protein–protein interaction
tumor suppression
Online Access:https://www.mdpi.com/2072-6694/14/3/505

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https://www.mdpi.com/2072-6694/14/3/505

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