Delineating effects of angiopoietin-2 inhibition on vascular permeability and inflammation in models of retinal neovascularization and ischemia/reperfusion

Delineating effects of angiopoietin-2 inhibition on vascular permeability and inflammation in models of retinal neovascularization and ischemia/reperfusion

IntroductionClinical trials demonstrated that co-targeting angiopoietin-2 (Ang-2) and vascular endothelial growth factor (VEGF-A) with faricimab controls anatomic outcomes and maintains vision improvements, with strong durability, through 2 years in patients with neovascular age-related macular dege...

Full description

Bibliographic Details
Main Authors: Jérémie Canonica, Richard Foxton, Marina Garcia Garrido, Cheng-Mao Lin, Sabine Uhles, Sumathi Shanmugam, David A. Antonetti, Steven F. Abcouwer, Peter D. Westenskow
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
angiopoietin-2
choroidal neovascularization
diabetic macular edema
neovascular age-related macular degeneration
vascular endothelial growth factor-A
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1192464/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1192464/full

Similar Items