TMEM106A transcriptionally regulated by promoter methylation is involved in invasion and metastasis of hepatocellular carcinoma

TMEM106A transcriptionally regulated by promoter methylation is involved in invasion and metastasis of hepatocellular carcinoma

Expression of transmembrane protein 106A (TMEM106A) has been reported to be dysregulated in several types of cancers. However, the role of TMEM106A in hepatocellular carcinoma (HCC) is still unknown. In the present study, we demonstrate that TMEM106A is markedly downregulated in HCC compared with no...

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Bibliographic Details
Main Authors: Shi Shiming, Wang Biao, Wan Jinglei, Song Lina, Zhu Guiqi, Du Junxian, Ye Luxi, Zhao Qianqian, Cai Jialiang, Chen Qing, Xiao Kun, He Jian, Yu Lei, Dai Zhi
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-06-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
hepatocellular carcinoma
transmembrane protein 106A
methylation
epithelial mesenchymal transition
metastasis
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022069

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https://www.sciengine.com/doi/10.3724/abbs.2022069

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