Generation of two lymphoblastoid-derived induced pluripotent stem cell (iPSC) lines from patients with phenylketonuria

Generation of two lymphoblastoid-derived induced pluripotent stem cell (iPSC) lines from patients with phenylketonuria

We employed a Sendai virus-based reprogramming method to transform human lymphoblastoid cell lines (LCL) derived from two individuals diagnosed with phenylketonuria (PKU) into induced pluripotent stem cells (iPSC). This reprogramming process involved the expression of the four Yamanaka factors: KLF4...

Full description

Bibliographic Details
Main Authors: Desi Veleva, Merve Ay, Dmitry A. Ovchinnikov, Andrew B.J. Prowse, Minal J. Menezes, Michael Nafisinia
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Stem Cell Research
Subjects:
Phenylketonuria
PKU
Human Induced pluripotent stem cells (hiPSC)
High throughput drug screening
Personalised medicine
Drug discovery
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506124001053

Internet

http://www.sciencedirect.com/science/article/pii/S1873506124001053

Similar Items