CTCF, Cohesin, and Chromatin in Human Cancer
It is becoming increasingly clear that eukaryotic genomes are subjected to higher-order chromatin organization by the CCCTC-binding factor/cohesin complex. Their dynamic interactions in three dimensions within the nucleus regulate gene transcription by changing the chromatin architecture. Such spati...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BioMed Central
2017-12-01
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Series: | Genomics & Informatics |
Subjects: | |
Online Access: | http://genominfo.org/upload/pdf/gi-2017-15-4-114.pdf |