A New Ligand-Based Method for Purifying Active Human Plasma-Derived Ficolin-3 Complexes Supports the Phenomenon of Crosstalk between Pattern-Recognition Molecules and Immunoglobulins.

Despite recombinant protein technology development, proteins isolated from natural sources remain important for structure and activity determination. Ficolins represent a class of proteins that are difficult to isolate. To date, three methods for purifying ficolin-3 from plasma/serum have been propo...

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Bibliographic Details
Main Authors: Aleksandra Man-Kupisinska, Mateusz Michalski, Anna Maciejewska, Anna S Swierzko, Maciej Cedzynski, Czeslaw Lugowski, Jolanta Lukasiewicz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4883783?pdf=render