Blood-Derived α-Synuclein Aggregated in the Substantia Nigra of Parabiotic Mice

As a pathological biomarker of Parkinson’s disease, α-synuclein is thought to be a prion-like protein, but evidence for the transmission of α-synuclein from blood to the brain is unclear. The goals of this study were to determine whether blood-derived α-synuclein could enter the brains of mice and w...

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Bibliographic Details
Main Authors: Xizhen Ma, Leilei Chen, Ning Song, Le Qu, Jun Wang, Junxia Xie
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/9/1287