Prediction of Back-splicing sites for CircRNA formation based on convolutional neural networks

Prediction of Back-splicing sites for CircRNA formation based on convolutional neural networks

Abstract Background Circular RNAs (CircRNAs) play critical roles in gene expression regulation and disease development. Understanding the regulation mechanism of CircRNAs formation can help reveal the role of CircRNAs in various biological processes mentioned above. Back-splicing is important for Ci...

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Bibliographic Details
Main Authors: Zhen Shen, Yan Ling Shao, Wei Liu, Qinhu Zhang, Lin Yuan
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Genomics
Subjects:
CircRNA
Back-splicing sites prediction
Deep learning
Convolutional neural networks
Batch normalization
Online Access:https://doi.org/10.1186/s12864-022-08820-1

Internet

https://doi.org/10.1186/s12864-022-08820-1

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