Glucocorticoids protect HEI-OC1 cells from tunicamycin-induced cell damage via inhibiting endoplasmic reticulum stress

Glucocorticoids protect HEI-OC1 cells from tunicamycin-induced cell damage via inhibiting endoplasmic reticulum stress

To analyze mechanisms of action of glucocorticoid treatment for endoplasmic reticulum stress (ERS) in sensorineural hearing loss (SNHL), we aimed to evaluate the expression and activation status of the protein kinase RNA-like ER kinase (PERK)–C/EBP homologous protein (CHOP) pathway, which is the maj...

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Bibliographic Details
Main Authors: Liu Zhibiao, Fei Bing, Xie Lisheng, Liu Jin, Chen Xiaorui, Zhu Wenyan, Lv Lingyun, Ma Wei, Gao Ziwen, Hou Jie, She Wandong
Format: Article
Language:English
Published: De Gruyter 2021-07-01
Series:Open Life Sciences
Subjects:
endoplasmic reticulum stress
perk–chop pathway
dexamethasone
mifepristone
Online Access:https://doi.org/10.1515/biol-2021-0057

Internet

https://doi.org/10.1515/biol-2021-0057

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