Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study

Causal association between subtypes of osteoarthritis and common comorbidities: A Mendelian randomisation study

Objective: To investigate the causal association between Osteoarthritis (OA) and five comorbidities: depression, tiredness, multisite chronic pain, irritable bowel syndrome (IBS) and gout. Design: This study used two-sample Mendelian Randomisation (MR). To select the OA genetic instruments, we used...

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Bibliographic Details
Main Authors: Will Thompson, Subhashisa Swain, Sizheng Steven Zhao, Anne Kamps, Carol Coupland, Changfu Kuo, Sita Bierma-Zeinstra, Jos Runhaar, Michael Doherty, Weiya Zhang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Osteoarthritis and Cartilage Open
Subjects:
OA
GO consortium
UK biobank
MR
Comorbidities
Online Access:http://www.sciencedirect.com/science/article/pii/S266591312300081X

Internet

http://www.sciencedirect.com/science/article/pii/S266591312300081X

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