Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compound
DPB162-AE is a valuable tool to study store-operated Ca2+ entry (SOCE), as this compound was developed as a 2-APB analog that inhibits SOCE more potently and more selectively than 2-APB itself. In addition to this, we showed that, in some conditions, DPB162-AE can deplete the endoplasmic reticulum C...
| Main Authors: | , , |
|---|---|
| 格式: | 文件 |
| 语言: | English |
| 出版: |
Elsevier
2017-06-01
|
| 丛编: | Data in Brief |
| 主题: | |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S2352340917301105 |
| _version_ | 1831750942812274688 |
|---|---|
| author | Mart Bittremieux Katsuhiko Mikoshiba Geert Bultynck |
| author_facet | Mart Bittremieux Katsuhiko Mikoshiba Geert Bultynck |
| author_sort | Mart Bittremieux |
| collection | DOAJ |
| description | DPB162-AE is a valuable tool to study store-operated Ca2+ entry (SOCE), as this compound was developed as a 2-APB analog that inhibits SOCE more potently and more selectively than 2-APB itself. In addition to this, we showed that, in some conditions, DPB162-AE can deplete the endoplasmic reticulum Ca2+ stores in intact cells, including the cervical carcinoma HeLa cell line and the diffuse large B-cell lymphoma SU-DHL-4 cell line. Here, we present data regarding the toxicity of DPB162-AE in HeLa and SU-DHL-4 cells. For further interpretation of the data presented in this article, please see the research article ‘DPB162-AE, an inhibitor of store-operated Ca2+ entry, can deplete the endoplasmic reticulum Ca2+ store’ (M. Bittremieux, J. V. Gerasimenko, M. Schuermans, T. Luyten, E. Stapleton, K.J. Alzayady, et al., 2017) [1]. |
| first_indexed | 2024-12-21T22:36:17Z |
| format | Article |
| id | doaj.art-eba1af73fd3e4849b3cbdf376b51a3ba |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-21T22:36:17Z |
| publishDate | 2017-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-eba1af73fd3e4849b3cbdf376b51a3ba2022-12-21T18:47:58ZengElsevierData in Brief2352-34092017-06-0112C919610.1016/j.dib.2017.03.034Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compoundMart Bittremieux0Katsuhiko Mikoshiba1Geert Bultynck2KU Leuven, Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine & Leuven Kanker Instituut, 3000 Leuven, BelgiumThe Laboratory for Developmental Neurobiology, Brain Science Institute, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, JapanKU Leuven, Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine & Leuven Kanker Instituut, 3000 Leuven, BelgiumDPB162-AE is a valuable tool to study store-operated Ca2+ entry (SOCE), as this compound was developed as a 2-APB analog that inhibits SOCE more potently and more selectively than 2-APB itself. In addition to this, we showed that, in some conditions, DPB162-AE can deplete the endoplasmic reticulum Ca2+ stores in intact cells, including the cervical carcinoma HeLa cell line and the diffuse large B-cell lymphoma SU-DHL-4 cell line. Here, we present data regarding the toxicity of DPB162-AE in HeLa and SU-DHL-4 cells. For further interpretation of the data presented in this article, please see the research article ‘DPB162-AE, an inhibitor of store-operated Ca2+ entry, can deplete the endoplasmic reticulum Ca2+ store’ (M. Bittremieux, J. V. Gerasimenko, M. Schuermans, T. Luyten, E. Stapleton, K.J. Alzayady, et al., 2017) [1].http://www.sciencedirect.com/science/article/pii/S2352340917301105DPB162-AECell toxicityCell linesCalcium |
| spellingShingle | Mart Bittremieux Katsuhiko Mikoshiba Geert Bultynck Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compound Data in Brief DPB162-AE Cell toxicity Cell lines Calcium |
| title | Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compound |
| title_full | Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compound |
| title_fullStr | Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compound |
| title_full_unstemmed | Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compound |
| title_short | Data on cytotoxicity in HeLa and SU-DHL-4 cells exposed to DPB162-AE compound |
| title_sort | data on cytotoxicity in hela and su dhl 4 cells exposed to dpb162 ae compound |
| topic | DPB162-AE Cell toxicity Cell lines Calcium |
| url | http://www.sciencedirect.com/science/article/pii/S2352340917301105 |
| work_keys_str_mv | AT martbittremieux dataoncytotoxicityinhelaandsudhl4cellsexposedtodpb162aecompound AT katsuhikomikoshiba dataoncytotoxicityinhelaandsudhl4cellsexposedtodpb162aecompound AT geertbultynck dataoncytotoxicityinhelaandsudhl4cellsexposedtodpb162aecompound |