HDAC2 links ubiquitination to tumor suppression in synovial sarcoma
The function of histone deacetylase 2 (HDAC2) in transcriptional regulation and its role in oncogenesis have been well established. Here we discuss a transcription-independent HDAC2 pathway controlling cancer-related protein stability via the mouse double minute 2 homolog (MDM2) ubiquitin ligase. In...
Päätekijät: | , |
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Aineistotyyppi: | Artikkeli |
Kieli: | English |
Julkaistu: |
Taylor & Francis Group
2021-05-01
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Sarja: | Molecular & Cellular Oncology |
Aiheet: | |
Linkit: | http://dx.doi.org/10.1080/23723556.2021.1914291 |