HDAC2 links ubiquitination to tumor suppression in synovial sarcoma

The function of histone deacetylase 2 (HDAC2) in transcriptional regulation and its role in oncogenesis have been well established. Here we discuss a transcription-independent HDAC2 pathway controlling cancer-related protein stability via the mouse double minute 2 homolog (MDM2) ubiquitin ligase. In...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Christina Cooley, Le Su
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Taylor & Francis Group 2021-05-01
Sarja:Molecular & Cellular Oncology
Aiheet:
Linkit:http://dx.doi.org/10.1080/23723556.2021.1914291