Role of insulin resistance and the gut microbiome on urine oxalate excretion in ob/ob mice

Abstract Ob/ob mice have recently emerged as a model for obesity‐related hyperoxaluria as they are obese and excrete more urine oxalate compared to wild type mice. Ob/ob mice are deficient of leptin and develop obesity with hyperphagia and hyperinsulinemia. We hypothesized that insulin resistance an...

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Bibliographic Details
Main Authors: Hong Xiang, Haoqing Chen, Yuanyuan Liu, Dylan Dodd, Alan C. Pao
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15357